期刊與審查論文
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Yung-Hsin Cheng, Shu-Hua Yang, Wen-Yu Su, Yu-Chun Chen, Kai-Chiang Yang, Winston Teng-Kuei Cheng, Shinn-Chih Wu, Feng-Huei Lin*, 2010, “Thermosensitive Chitosan- Gelatin-Glycerol Phosphate Hydrogels as a Cell Carrier for Nucleus Pulposus Regeneration: An In Vitro Study”, Tissue Engineering Part A, 16:695-703
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2.
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Wen-Yu Su, Yu-Chun Chen, Feng-Huei Lin*, 2010, “Injectable Oxidized Hyaluronic Acid/Adipic Acid Dihydrazide Hydrogel for Nucleus Pulposus Regeneration”, Acta Biomaterialia, 6:3044–55.
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3.
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Wen-Yu Su, Ko-Hua Chen, Yu-Chun Chen, Yen-Hsien Lee, Ching-Li Tseng, Feng-Huei Lin*, 2011, “An Injectable Oxidated Hyaluronic Acid/Adipic Acid Dihydrazide Hydrogel as a Vitreous Substitute”, Journal of Biomaterials Science, Polymer edition, 22:1777-97
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4.
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Yu-Chun Chen, Wen-Yu Su, Shu-Hua Yang, Amit Gefen, Feng-Huei Lin*, 2012, “In Situ Forming Hydrogels Composed of Oxidized High Molecular Weight Hyaluronic Acid and Gelatin for Nucleus Pulposus Regeneration”, Acta Biomaterialia, 9:5181-93.
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5.
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Wen-Yu Su, Yu-Chun Chen, Feng-Huei Lin*, “A New Type of Biphasic Calcium Phosphate Cement as a Gentamicin Carrier for Osteomyelitis”, Evidence-Based Complementary and Alternative Medicine, 2013 (Article ID 801374)
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6.
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Chih-Hung Chang*, Yuan-Ming Hsu, Yu-Chun Chen, Feng-Huei Lin, Subramaniam Sadhasivam, Siow-Tung Loo, Sivasubramanian Savitha, 2014, “Anti-Inflammatory effects of hydrophilic and lipophilic statins with hyaluronic acid against LPS-induced inflammation in porcine articular chondrocytes”, Journal of Orthopaedic Research, 32(4): 557-65
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7.
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Karl Wu#, Yu-Chun Chen#, Yuan-Ming Hsu, Chih-Hung Chang*. 2016, March. Enhancing Drug Release from Antibiotic-loaded Bone Cement Using Porogens. Journal of the American Academy of Orthopaedic Surgeons, 24(3): 188–195. (#These authors contributed equally to this work.)
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8.
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M.H. Hu, K.C. Yang , Y.H. Sun, Y.C. Chen, S.H. Yang*, and F.H. Lin. 2017, Nov. In situ forming oxidised hyaluronic acid/adipic acid dihydrazide hydrogel for prevention of epidural fibrosis after laminectomy. Eurp Cell Mater, 13(34):307-320
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9.
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Chia-Chun Chen, Chu-Yun Hsiao, Yao-Horng Wang, Yu-Chun Chen, Chih-Hung Chang*, Hsu-Wei Fang*. 2017, Sep. A comparison of distinct bone marrow-derived cells on cartilage tissue engineering. Journal of the Taiwan Institute of Chemical Engineers, 78:32-38
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10.
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Yeong-Jang Chen, Jwo-luen Pao, Chiang Sang Chen, Yu-Chun Chen, Chun-Chien Chang, Fang-Ming Hung, and Chih-Hung Chang*. 2017. Jan. Evaluation of New Biphasic Calcium Phosphate Bone Substitute: Rabbit Femur Defect Model and Preliminary Clinical Results. Journal of Medical and Biological Engineering, 37(1): 85–93.
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11.
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Yu-Chun Chen, Yuan-Ming Hsu, Kinn Poay Tan, Chih-Hung Chang*. 2018. Oct. Intraarticular injection for rabbit knee Osteoarthritis: Effectiveness among hyaluronic acid, platelet-rich plasma, and mesenchymal stem cells. Journal of the Taiwan Institute of Chemical Engineers, 91:138–145.
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12.
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Yu-Chun Chen, Yu-Wei Chang, Kinn Poay Tan, Yi-Shan Shen, Yao-Horng Wang, Chih-Hung Chang*. 2018, Nov. Can mesenchymal stem cells and their conditioned medium assist inflammatory chondrocytes recovery? PLOS ONE, 13(11):e0205563.
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Yu-Chun Chen, Chih-Hung Chang*. 2020 July. Clinical Application of Mesenchymal Stem Cells for Cartilage Regeneration. Journal Plastic and Aesthetic Research, 7:49.
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賴建成、陳郁君、雷涵媮、張至宏*。2020 Nov. 退化性膝關節炎再生醫學治療及醫病共享決策之應用Applications of Shared Decision Making for Regenerative Treatment of Knee Osteoarthritis. Formosan Journal of Medicine, 24:6, 659-664.
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15.
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Karl Wu, Yu-Chun Chen, Shang M Lin, Chih-Hung Chang*. 2021 May. In vitro and in vivo effectiveness of a novel injectable calcitonin-loaded collagen/ceramic bone substitute. Journal of Biomaterials Applications. 35(10):1355-1365. doi: 10.1177/0885328221989984. Epub 2021 Jan 31.
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16.
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Yu-Chun Chen, Hwa-Chang Liu, Feng-Huei Lin and Chih-Hung Chang*. 2021 March. Development of Engineered Cartilage Product from Bone Marrow Mesenchymal Stem Cells: An Example in Taiwan. Journal of Musculoskeletal Research VOL. 24, NO. 01
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17.
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Hung-Hsuan Chen#, Yu-Chun Chen#, San-Ni Yu, Wan-Ling Lai, Yi-Shan Shen, Pei-Chun Shen, Siao-Han Lin, Chih-Hung Chang*, Shing-Mou Lee*. 2022 Jan. Infrapatellar fat pad–derived mesenchymal stromal cell product for treatment of knee osteoarthritis: a first-in-human study with evaluation of the potency marker. Cytotherapy. 24(1):72-85. doi: 10.1016/j.jcyt.2021.08.006. Epub 2021 Oct 22
# contributed equally
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18.
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Yu-Chun Chen, Hsiu-Jung Liao, Yuan-Ming Hsu, Yi-Shan Shen, and Chih-Hung Chang*. 2022 Apr. 05. Delivery of Mesenchymal Stem Cell in Dialdehyde Methylcellulose-Succinyl-Chitosan Hydrogel Promotes Chondrogenesis in a Porcine Model. Polymers 2022, 14(7), 1474; https://doi.org/10.3390/polym14071474
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19.
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Chen, Hung-Hsuan#; Chen, Yu-Chun#; Yu, San-Ni; Lai, Wan-Ling; Shen, Yi-Shan; Shen, Pei-Chun; Lin, Siao-Han; Chang, Chih-Hung; Lee, Shing-Mou*# contributed equally.2022 Jan. Infrapatellar fat pad-derived mesenchymal stromal cell product for treatment of knee osteoarthritis: a first-in-human study with evaluation of the potency marker. Cytotherapy 2022, 24(1),72-85.
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研討會論文
1.
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Yu-Chun Chen, Feng-Huei Lin*, 2007, “In Vitro Biocompatible Evalua-tion of Nucleus Pulposus Cells Cultured in Hyaluronan/Alginate Beads” 4th European Symposium on Biopolymers (ESBP), Oral presentation. |
2.
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Yu-Chun Chen, Wen-Yu Su, Feng-Huei Lin*, 2009, “Injectable Hy-aluronic Acid / Adipic Acid Dihydrazide for Nucleus Pulposus Regeneration”, Annual Meeting of Formosa Association of Regenerative Medicine Oral presentation |
3.
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Yu-Chun Chen, Wen-Yu Su, Feng-Huei Lin*, 2010, “In Situ Forming Hyaluronic Acid Hydrogel for Nucleus Pulposus Regeneration : Rheological Properties and Gene Expression”, International Symposium of Materials on Regenerative Medicine (ISOMRM), Oral presentation |
4.
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Yu-Chun Chen, Wen-Yu Su, Feng-Huei Lin*, “Rheological Characterization of Injectable Hyaluronic Acid Hydrogel for Nucleus Pulposus Regeneration”, NHRI Research Day, Mar., 2010, Zhunan, Taiwan, Poster Presentation (Excellent Poster Award) |
5.
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Yu-Chun Chen, Wen-Yu Su, Feng-Huei Lin*, 2011, “In Situ Forming Hyaluronic Acid Hydrogel for Nucleus Pulposus Regeneration: Rhe-ological Properties and Gene Expression”, Tissue Engineering International & Regenerative Medicine Society (TERMIS), Oral presentation |
6.
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Wen-Yu Su, Yu-Chun Chen, Feng-Huei Lin*, “An Injectable Oxidated Hyaluronic Acid/Adipic Acid Dihydrazide Hydrogel as a Vitreous Substitute”, NHRI Research Day, Mar., 2011, Zhunan, Taiwan, Poster presentation |
7.
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Yu-Chun Chen, Wen-Yu Su, Feng-Huei Lin*, “Injectable Hyaluronic Acid-Gelatin Hydrogel for Nucleus Pulposus Regeneration: Viscoelastic Properties, Cell Behavior, and Gene Expression Analysis”, NHRI Research Day, Mar., 2012, Zhunan, Taiwan, Poster presentation |
8.
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Yu-Chun Chen, Wen-Yu Su, Feng-Huei Lin*, “In Situ Forming Hyaluronic Acid-based Hydrogel for Nucleus Pulposus Regeneration: An Experimental Study Using an Animal Model”, NHRI Research Day, Mar., 2013, Zhunan, Taiwan, Oral Presentation (Elected Paper Award) |
9.
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Yu-Chun Chen, Kinn Poay Tan, Chih-Hung Chang*, 2014, “Bone Marrow Mesenchymal Stem Cells Reduced LPS- Induced Inflammatory Response in Chondrocytes”, World Congress on Preventive and Regenerative Medicine (WCPRM), Oral presentation. |
10.
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Yu-Chun Chen, Yuan-Ming Hsu, Ruo-Yu Chen, Chih-Hung Chang*, 2014, “Acellular Cartilage Matrix for Cartilage Tissue Engineering: Preparation, Characterization, and Biocompatibility Evaluation”, World Congress on Preventive and Regenerative Medicine (WCPRM), Oral presentation. |
11.
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Yu-Chun Chen, Yuan-Ming Hsu, Kinn Poay Tan, Chih-Hung Chang*, 2015, “Comparison of Platelet-rich Plasma or Hyaluronic Acid with/without Bone Marrow Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis in a Rabbit Model”, Annual Meeting of Formosa Association of Regenerative Medicine, Oral presentation. |
12.
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Yu-Chun Chen, Ruo-Yu Chen, Yuan-Ming Hsu and Chih-Hung Chang*, 2016, “Acellular Cartilage Matrix Combined with Chtosan Cellulose Hydrogel for Cartilage Regeneration: Cell-compatibility and Gene Expression Analysis”, 2016 Tissue Engineering and Regenerative Medicine International Society- Asia Pacific Meeting, Oral presentation. |
13.
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Yu-Chun Chen, Yi-Shan Shen, Feng- Hui Lin, Chih-Hung Chang*, 2016, “In Situ Forming Thermosensitive Hydrogel Combined with ACM for One-stage Cartilage Defect Treatment”, Annual Symposium on Biomedical Engineering and Technology Engineering and Technology, Poster presentation. |
14.
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Yu-Chun Chen, Ruo-Yu Chen, Yi-Shan Shen,Yuan-Ming Hsu and Chih-Hung Chang*, 2017, “Acellular Cartilage Matrixc Combined with Chitosan Cellulose Hydrogel for Cartilage Regeneration: Cellcompatibility and Gene Expression Analysis”, International Conference of Development Biology, Stem Cell and Regenerative Medicine, Poster presentation. |
15.
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Yu-Chun Chen, Wen-Yu Su, Yi-Shan Shen, Feng- Hui Lin and Chih-Hung Chang*, 2018, “Hyaluronic Acid-based Thermosensitive Hydrogel Combined with Acellular Cartilage Matrix for Cartilage Defect Treatment” IUPESM 2018 - World Congress on Medical Physics & Biomedical, Oral presentation |
16.
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Yu-Chun Chen, Hung-Hsuan Chen, Ni-En Jiang, Yi-Shan Shen, Hsiu-Jung Liao, Shing-Mou Lee, Chih-Hung Chang. 2021. Anti-inflammation effect of infrapatellar fat pad mesenchymal stem cell for osteoarthritis treatment. Tissue Engineering and Regenerative Medicine International Society (TERMIS) World Congress, Maastricht, Netherlands. Online Meeting.
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17.
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Ching-Wen Chang, Kuo-Teng Hsu, Yu-Chun Chen*. 2022. Development of Quercetin contained Hyaluronic Acid Hydrogel as a Vitreous Substitute. Annual Meeting of Biomaterials and Controlled Releases Society in Taiwan. Hsinchu, Taiwan. Poster presentation.
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18.
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Yun-Qing Sun, Yan-Ping Song, Yu-Chun Chen*. 2022. Anti-Inflammation Ability Evaluation of Different Cultivation Microenvironment Mesenchymal Stem Cell Derived Exosome. Annual Meeting of Biomaterials and Controlled Releases Society in Taiwan. Hsinchu, Taiwan. Poster presentation
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19.
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Yu-Ping Chen, Chih-Hung Chang, Feng-Huei Lin, Yu-Chun Chen*. 2022. The Study of Extracellular Vesicles Derived from Micromass Cultivated MSC for Cartilage Matrix Synthesis Promotion. MRS-Taiwan Annual Meeitng, Miaoli, Taiwan. Poster presentation.
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發明專利
1.
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Feng-Huei Lin, Wen-Yu Su, Yu-Chun Chen, Ko-Hua Chen. “Cross-linked oxidized hyaluronic acid for use as a vitreous substitute.” United States Patent US8,197,849 B2. 2012/06~2030/08
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2.
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林峯輝、蘇文郁、陳郁君、陳克華,“交聯氧化玻尿酸作為眼球玻璃體之替代物”,中華民國TWI389713,專利期間2013/03~2030/10
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3.
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林峰辉、苏文郁、陈克华、陈郁君,“交联氧化透明质酸作为眼球玻璃体之替代物”,中華人民共和國CN 102762647 A,專利期間2014/12~2032/10
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4.
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Feng-Huei Lin, Wen-Yu Su, Yu-Chun Chen, Ko-Hua Chen. “Cross-linked oxidized hyaluronic acid for use as a vitreous substitute.” Australian Patent AU2011215775B2. 2012/04~2031/02
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5.
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Feng-Huei Lin, Wen-Yu Su, Yu-Chun Chen, Ko-Hua Chen. “Cross-linked oxidized hyaluronic acid for use as a vitreous substitute.” Patent Cooperation Treaty (PCT) WO2011100469A1. 2011/08~2031/02
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6.
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Feng-Huei Lin, Wen-Yu Su, Yu-Chun Chen, Ko-Hua Chen. “Cross-linked oxidized hyaluronic acid for use as a vitreous substitute.” Spain Patent ES2535115T3. 2015/05~2031/02
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7.
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Feng-Huei Lin, Wen-Yu Su, Yu-Chun Chen, Ko-Hua Chen. “Cross-linked oxidized hyaluronic acid for use as a vitreous substitute.” European Patent EP2534200B1. 2015/04~2031/02
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8.
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Feng-Huei Lin, Wen-Yu Su, Yu-Chun Chen, Ko-Hua Chen. “Cross-linked oxidized hyaluronic acid for use as a vitreous substitute.” Canada Patent CA2786911C. 2015/10~2031/02
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9.
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Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin. “Gamma-polyglutamic acid-based ocular irrigating solutions” Patent Cooperation Treaty (PCT) WO2011127221A1. 2011/10~2031/04
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10.
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Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin. “Gamma-polyglutamic acid-based ocular irrigating solutions” European Patent EP2555780B1. 2016/02~2031/04
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11.
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陈郁君、苏文郁、李彦贤、陈克华、林峰辉,“γ-聚麸胺酸类眼科手术冲洗液”,中華人民共和國CN102939092B. 2015/10~2031/04
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12.
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Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin. “Gamma-polyglutamic acid-based ocular irrigating solutions” Australian Patent AU2011237671B2. 2014/04~2031/04
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13.
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Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin. “Gamma-polyglutamic acid-based ocular irrigating solutions” Canada Patent CA2794563C. 2014/11~2031/04
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14.
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林峯輝、陳郁君、蘇文郁、李彥賢、陳克華,“γ-聚麩胺酸類眼科手術沖洗液”,中華民國TWI482639B. 2015/05~2031/04
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15.
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Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin. “Gamma-polyglutamic acid-based ocular irrigating solutions” United States Patent US9457000B2. 2016/10~2031/06
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