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認證計畫專區

賴盈宏老師個人網站

【個人基本資料】

中文姓名:賴盈宏
英文姓名:Lai Yin-Hung
聯絡電話:037-382206
 E-maillaiyh@nuu.edu.tw

1

 

【主要學歷】

畢/肆業學校

國別

主修學門系所

學位

國立台灣大學

中華民國

生物機電工程學系

工學士

國立清華大學

中華民國

化學系

博士(物理化學組)

中央研究院

中華民國

基因體研究中心

中研院延聘博士後研究學者

(2014-2015)

Stanford University

USA

Chemistry

Postdoctoral Research Fellow

(2016-2018)

ETH Zürich

Switzerland

Department of Chemistry and Applied Biosciences

Postdoctoral Research Fellow

(2018-2020)

 

【研究專長】

質譜儀開發及其於生醫與環境科學之應用

 

【負責實驗室】

A2-446 質譜實驗室Bioanalytical & Environmental Mass Spectrometry Laboratory

 

【學術著作】

期刊與審查論文

 

At NUU

28

Cao, J.-L., Wang, Y.-S., Lai, Y.-H.,* Antioxidant properties and colorectal cancer cell cytotoxicity of phenolics occurring in Calvatia lilacina (puffball mushroom). In preparation

27

Lai, Y.-H.,* Leung, W., Chang, P.-H., Zhou, W.-X., Wang, Y.-S.,* Structural identification of carbohydrate isomers using ambient near-infrared-assisted dissociation. Anal. Chim. Acta, 1264, 341307 (2023)

[SCI impact factor = 6.911, CHEMISTRY, ANALYTICAL: 10/87]

26

Lai, Y.-H.,* Zhou, W.-X., Chi, K.-H., Hsu, Y.-C., Weng, Y.-M., Organochlorine pesticides in estuarine sediments of protected wetlands, Taiwan using HRGC/HRMS and GC-ECD. J. Chin. Chem. Soc., 70, 770-778 (2023)

[SCI impact factor = 1.753, CHEMISTRY, MULTIDISCIPLINARY: 135/180]

25

Martínez-Jarquín, S., Begley, A., Lai, Y.-H., Bartolomeo, G. L., Pruška, A., Zenobi, R.,* Aptapaper─An Aptamer-Functionalized Glass Fiber Paper Platform for Rapid Upconcentration and Detection of Small Molecules. Anal. Chem., 94, 5651-5657 (2022) [SCI impact factor = 8.008, CHEMISTRY, ANALYTICAL: 7/87]

24

Lai, Y.-H.,* Wang, Y.-S.,* Advances in High-Resolution Mass Spectrometry Techniques for Analysis of High Mass-to-Charge Ions. Mass Spectrom. Rev. e21790, doi.org/10.1002/mas.21790 (2022) [SCI impact factor = 9.011, SPECTROSCOPY: 3/43]

23

Chang, H.-W.,* Dong, C.-L., Chen, Y.-H., Xu, Y.-Z., Huang, T.-C., Chen, S.-C., Liu, F.-J., Lai, Y.-H.,* Tsai, Y.-C.,* Extended Graphite Supported Flower-like MnO2 as Bifunctional Materials for Supercapacitors and Glucose Sensing. Nanomaterials, 11, 2881 (2021) [SCI impact factor = 5.719, PHYSICS, APPLIED: 37/161]

22

Du, Y., Brumaud, C.,* Winnefeld, F., Lai, Y.-H., Habert, G., Mechanisms for efficient clay dispersing effect with tannins and sodium hydroxide. Colloids Surf. A Physicochem. Eng. Asp., 127589 (2021) [SCI impact factor = 5.518, CHEMISTRY, PHYSICAL: 64/162]

21

Hsiao, C.-H., Lai, Y.-H., Kuo, S.-Y., Cai, Y.-H., Lin, C.-H., Wang, Y.-S.,* A Dynamic Data Correction Method for Enhancing Resolving Power of Integrated Spectra in Spectroscopic Analysis. Anal. Chem., 92, 12763-12768 (2020) [SCI impact factor = 8.008, CHEMISTRY, ANALYTICAL: 8/87]

20

van den Berg, J. L., Lai, Y.-H., Wadsworth, G. A., Lamberti, W. A., Woo, H., Raman, S., Zare, R. N.,* Spraying model PAHs on charged TiO2 surface for high-efficiency degradation. Energy Fuels 34, 4289-4295 (2020) [SCI impact factor = 4.654, ENGINEERING, CHEMICAL: 57/143]

19

Yin, H., Zheng, L.-Q.,* Fang, W., Lai, Y.-H., Porenta, N., Goubert, G., Zhang, H., Su, H.-S., Ren, B., Richardson, J. O.,* Li, J.-F.,* and Zenobi, R.,* Nanometer scale spectroscopic visualization of catalytic sites during a hydrogenation reaction on a Pd/Au bimetallic catalyst. Nat. Catal. 3, 834-842 (2020) [SCI impact factor = 40.706, CHEMISTRY, PHYSICAL: 2/162]

Before NUU

18

Zhou, Z., Yan, X., Lai, Y.-H., Zare, R.N.,* Fluorescence Polarization Anisotropy in Microdroplets, J. Phys. Chem. Lett. 9, 2928-2932 (2018)

17

Yan, X., Lai, Y.-H., Zare, R. N.,* Preparative microdroplet synthesis of carboxylic acids from aerobic oxidation of aldehydes. Chem. Sci. 9, 5207-5211 (2018)

16

Sathyamoorthi, S., Lai, Y.-H., Bain, R. M., Zare, R.N.,* Mechanistic Analysis of the C–H Amination Reaction of Menthol by CuBr2 and Selectfluor®. J. Org. Chem. 83, 5681-5687 (2018)

15

Lai, Y.-H., Sathyamoorthi, S., Bain, R. M., Zare, R.N.,* Microdroplets Accelerate Ring Opening of Epoxides. J. Am. Soc. Mass Spectrom. 29, 1036-1043 (2018)

14

Lai, Y.-H., Zhou, Z., Basheer, C., Zare, R.N.,* Upgrading asphaltenes by oil droplets striking a charged TiO2-immobilized paper surface. Energy Fuels 31, 12685-12690 (2017)

13

Lee, H., Lai, Y.-H., Ou, Y.-M., Tsao, C.-W., Jheng, Y.-J., Kuo, S.-Y., Chang, H.-T., Wang, Y.-S.,* Enhancing carbohydrate ion yield by controlling crystalline structures in matrix-assisted laser desorption/ionization mass spectrometry. Anal. Chim. Acta 994, 49-55 (2017)

12

Lai, Y.-H.,* and Wang, Y.-S., Matrix-assisted laser desorption/ ionization mass spectrometry: mechanistic studies and methods for improving the structural identification of carbohydrates. Mass Spectrom (Tokyo) 6(3), S0072 (2017)

11

Jansson, E. T., Lai, Y.-H., Santiago, J. G., Zare, R. N.,* Rapid hydrogen-deuterium exchange in liquid droplets. J. Am. Chem. Soc. 139, 6851-6854 (2017)

10

Primadona, I., Lai, Y.-H., Capangpangan, R. Y., Obena, R. P., Tseng, M.-C., Huang, M.-F., Chang, H.-T., Li, S.-T., Wu, C.-Y., Chien, W.-T., Lin, C.-C., Wang, Y.-S.,* Chen, Y.-J.,* Functionalized HgTe nanoparticles promote laser-induced solid phase ionization/dissociation for comprehensive glycan sequencing. Analyst 141, 6093-6103 (2016)

9

Ou, Y.-M., Tsao, C.-W., Lai, Y.-H., Lee, H., Chang, H.-T., Wang, Y.-S.,* Preparation of homogeneous MALDI samples for quantitative applications. J. Vis. Exp. 116 (2016)

8

Lai, Y.-H., Cai, Y. H., Lee, H., Ou, Y.-M., Hsiao, C.-H., Tsao, C.-W., Chang, H.-T., Wang, Y.-S.,* Reducing spatial heterogeneity of MALDI samples with Marangoni flows during sample preparation. J. Am. Soc. Mass Spectrom. 27, 1314-1321 (2016)

7

Wang, C.-C., Lai, Y.-H., Ou, Y.-M., Chang, H.-T., Wang, Y.-S.,* Critical factors determining the quantification capability of matrix-assisted laser desorption/ionization– time-of-flight mass spectrometry. Philos. Trans. R. Soc. A-Math. Phys. Eng. Sci. 374, (2016)

6

Cai, Y.-H., Lai, Y.-H., Wang, Y.-S.,* Coupled space- and velocity-focusing in time-of-flight mass spectrometry-a comprehensive theoretical investigation. J. Am. Soc. Mass Spectrom. 26, 1722-1731 (2015)

5

Lai, Y.-H., Chen, B.-G., Lee, Y.-T., Wang, Y.-S.,* Lin, S.H.,* Contribution of thermal energy to initial ion production in matrix-assisted laser desorption/ionization observed with 2,4,6-trihydroxyacetophenone. Rapid Commun. Mass Spectrom. 28, 1716-1722 (2014)

4

Chu, K.-Y., Lee, S., Tsai, M.-T., Lu, I.-C., Dyakov, Y. A., Lai, Y.-H., Lee, Y.-T., Ni, C.-K.,* Thermal proton transfer reactions in ultraviolet matrix-assisted laser desorption/ionization. J. Am. Soc. Mass Spectrom. 25, 310-318 (2014)

3

Wu, C.-L., Wang, C.-C., Lai, Y.-H., Lee, H., Lin, J.-D., Lee, Y.-T., Wang, Y.- S.,* Selective enhancement of carbohydrate ion abundances by diamond nanoparticles for mass spectrometric analysis. Anal. Chem. 85, 3836-3841 (2013)

2

Lai, Y.-H., Wang, C.-C., Chen, C.W., Liu, B.-H., Lin, S.H., Lee, Y.-T., Wang, Y.-S.,* Analysis of initial reactions of MALDI based on chemical properties of matrixes and excitation condition. J. Phys. Chem. B 116, 9635-9643 (2012)

1

Lai, Y.-H., Wang, C.-C., Lin, S.H., Lee, Y.-T., Wang, Y.-S.,* Solid-phase thermodynamic interpretation of ion desorption in matrix-assisted laser desorption/ionization. J. Phys. Chem. B 114, 13847-13852 (2010)

 

研討會論文

8.

賴盈宏, Selective trace analysis using aptamer - functionalized sampling stripes hyphenated with ambient mass spectrometry, 第十七屆台灣質譜年會暨學術研討會, 國立嘉義大學, 2020

7.

Lai, Y.-H., Bartolomeo, G. L., Gyr, L., Marchand, A., Zenobi, R.,* Hyphenating Silica- and Paper-based Analytics and Ambient Mass Spectrometry as a High-throughput Readout for Trace Environmental Toxins, Status-Report Meeting Merck Lab @ TU Darmstadt, Germany, 2019

6.

Lai, Y.-H., Zhou, Z., Basheer, C., Zare, R.N.,* Acceleration of TiO2-catalyzed oil upgrading in microdroplets, 253rd American Chemical Society National Meeting & Exposition San Francisco, California, 2017

5.

Lai, Y.-H., Matrix-assisted laser desorption/ ionization mass spectrometry: mechanistic studies and its application in carbohydrate analysis, International Biological mass spectrometry symposium, Tokyo, Japan, 2016 Invited Keynote Speaker

4.

Lai, Y.-H., Ou, Y.-M., Lee, H., Wang, Y.-S.,* Enhancing ion abundances of oligosaccharides by the Marangoni effect in MALDI mass spectrometry, 63rd ASMS Conference on Mass Spectrometry and Allied Topics St. Louis, Missouri, 2015

3.

Lai, Y.-H., Cai, Y.-H., Lee, H., Wang, Y.-S.,* Enhancing ion abundances and spatial homogeneity of glycans by regulating the substrate temperature in MALDI MS: a physical chemistry perspective, MSACL Mass Spectrometry: Applications to the Clinical Lab 2015 US San Diego, California, 2015 Young Investigator Grantee

2.

Lai, Y.-H., Lee, H., Cai, Y.-H., Wang, Y.-S.,* Manipulating alkali metal ion distribution in MALDI with sample preparation protocols as revealed by dual-polarity time-of-flight imaging mass spectrometry, 20th international mass spectrometry conference Geneva, Switzerland, 2014 Outstanding Post-Doctoral Researchers Conference Travel Grant

1.

Lai, Y.-H., Lee, H., Cai, Y.-H., Wang, Y.-S.,* Enhancement of ion abundances and spatial homogeneity of carbohydrates in MALDI by regulating the substrate temperature, 5th Asia Oceania Mass Spectrometry Conference & the Young Scientist Forum Beijing, China, 2014 SHIMADZU Travel Award

 

 

 

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